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KMID : 0358419750180060387
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Korean Journal of Obstetrics and Gynecology
1975 Volume.18 No. 6 p.387 ~ p.393
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On the Ultrastructure of Squamous Cell Carcinoma of Uterine Cervix
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Abstract
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The author studied the ultrastructures of the uterine cervical epithelial cells in 8 squamous cell carcinoma cases.
The results were as follow:
1) The cellular borders were irregular and showed microvilli-like structure.
2) Nuclei were considerably large and chromatin patterns were markedly heterochromatic. Nucleoli were also enlarged and prominent.
3) Most areas of cytoplasm were filled with increased tonofilaments in certain cells. Also noted were increase of free ribosome, decrease of rER, Swelling of mitochondria with variation in their size, and atrophy of Golgi. complex.
4) Basement membranes were partially discontinued, from where epithelial cells were protruded.
5) These changes may regard as a morphologic expression of #cellular dedifferentiation, and embryonic cells or blasts also show similar structures, which would be the difficult point in differentiation of malignant tumor cells from embryonic cells or blasts.
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